Oak Park Staff
| Ewen Mullins |
|
|
|---|---|---|
| Title | Senior Research Officer | |
| Job Remit | Impact assessment of GM crops | |
| Phone Number | +353 59 9170298 | |
| ewen.mullins@teagasc.ie | ||
| Programme website | ||
Research Programme
For centuries, farmers have been
improving and modifying their crops. Through the process
of selective breeding, specific traits are identified
and a hybrid line is created that expresses the desired
agronomic character (e.g. high yield, disease
resistance). This conventional form of breeding has had
great success but by its nature has also imposed many
restrictions. Modern day biotechnology provides a means
to accelerate this pace of discovery and over the last
decade especially, the application of this science to
crop improvement has provided a tremendous insight into
its potential.
Now, through biotechnology, a gene of interest that
originates in bacteria, fungi, another plant can now be
inserted into the genome of a specific crop. As a
consequence, certain crops now possess characteristics
that previously would have been considered unattainable.
For example; potato varieties have been developed with
resistance to potato blight disease after the transfer
of genes from a number of wild potato species taken from
central America, while 'Golden Rice' has been generated
with elevated levels of vitamin A after the transfer of
a number of daffodil genes into a commercial rice
variety to combat childhood illnesses.
Though potentially advantageous, the production of these
genetically modified (GM) plants has invoked public
concern, in regard to the perceived environmental
impacts and other issues associated with the coexistence
of GM and non-GM crops. Our research is focussed on
addressing these concerns.
At present, we are investigating the environmental
impact of a GM potato line that has been developed with
durable resistance to potato late blight disease;
causative agent of the Irish Potato Famine. This work is
being conducted at Oak Park under license by the
EPA and is part of a larger European funded project
('AMIGA') to
assess the impacts of GM crops on the agro-ecosystem. In parallel, we are conducting a gene discovery
programme in wheat, with the goal of isolating genes
that could provide durable resistance to the important
leaf disease Septoria tritici
blotch. This is critically important in light
of the decreased efficacy of existing fungicide regimes
against
Septoria. We have also
developed a novel technology platform to transfer genes
of interest into target species. Based on a non-Agrobacterium
spp. our system (termed
Ensifer-mediated transformation, 'EMT') bypasses the existing quagmire of patent
restrictions that exist with current gene transfer
techniques.
We have recently concluded two studies. One
was focussed on developing cost-effective production
measures for GM herbicide tolerant (GMHT) oilseed rape
in coexistence with non-GM oilseed rape cultivars. The
second study was to assess the environmental impact of
Irish-specific GM crops using a novel biodiversity index
(termed CINMa) which factors in the impact of a crop's
management on different ecological zones (e.g. field,
hedgerow etc...) through time. The objective of this
work was to design a research methodology to assist in
the completion of GM crop risk assessments as per the
general surveillance component of EU legislation
2001/18.
Post-doctoral Researchers
- Sinead Phelan
- Assessing and monitoring the impacts of GM
potato on Irish agro-ecosystems (AMIGA)
Current post-graduate students
- Steven Rudder - Developing a novel technology platform for the transformation of plant cells
- Dheeraj Rathore - Expanding the strategic potential of Ensifer-mediated transformation in plant species
- Rupali Shinde - Producing high value products through the bioconversion of wheat
- Aoife O'Driscoll - Identifying sources of genetic resistance against Septoria tritici
- Moses Nyongesa - Testing the efficacy of genes isolated from wild potato species to confer robust resistance to potato blight
Current Projects
- Evaluating the potential of non-Agrobacterium spp. to facilitate gene transfer into main crops (RMIS 6188; funded through Science Foundation Ireland 2011 Research Frontiers Programme)
- Assessing and monitoring the impacts of GM crops on agro-ecosystems, 'AMIGA' (RMIS 6269, funded through the European Commission's 7th Framework)
- Assessing the potential biodiversity impacts of GM crop cultivation in Ireland (RMIS 5621; funded through EPA STRIVE)
- Co-existence of GM and non-GM oilseed rape in Irish tillage systems (RMIS 5629; funded through DAFF Stimulus Fund)
- Systems approach to the control of late
blight disease in potato (RMIS 5758; funded
through DAFF Stimulus Fund)
Select Publications
- Collier, M. and Mullins, E. (2013). Potential for longevity of novel genetically modified herbicide-tolerant traits in the Irish landscape. Irish Geography, DOI:10.1080/00750778.2013.775768
- Ali, S.S., Nugent, B., Mullins, E. and
Doohan, F. (2013). Insights from the fungus
Fusarium oxysporum
point
to
high affinity glucose transporters as targets for enhancing ethanol production from lignocellulose. PLOS One, January, Volume 8, Issue 1, e54701. - Collier, M. and Mullins, E. (2012) Assessing the impact of pollen-mediated gene flow from GM herbicide tolerant Brassica napus into common wild relatives in Ireland. Biology and Environment, Proceedings of the Royal Irish Academy, Vol. 112B, Issue 3, 257 - 266.
- Spink, J., Mullins, E. and Berry, P. (2012) Potential for Yield Improvement. In: Sayigh A (ed.) Comprehensive Renewable Energy, Vol. 5, p. 293-303. Oxford: Elsevier, ISBN: 978-0-08-087872-0.
- Shahin, S.A., Khan, M., Mullins, E. and Doohan, F. (2012). The effect of wheat genotype on ethanol production from straw and the implications for multifunctional crop breeding. Biomass and Bioenergy, Vol.42, 1-9.
- Shahin, S.A., Khan, M., Fagan, B., Mullins, E. and Doohan, F. (2012). Exploiting the inter-strain divergence of Fusarium oxysporum for microbial bioprocessing of lignocellulose to bioethanol. Applied Microbiology and Biotechnology Express, 2:16-19.
- Wendt, T., Doohan, F and Mullins, E. (2012). Production of Phytophthora infestans-resistant potato (Solanum tuberosum) utilising Ensifer adhaerens OV14. Transgenic Research, 21(3), 567-578.
- Wendt, T., Doohan, F., Wincklemann, D. and Mullins, E. (2011). Gene transfer into Solanum tuberosum via Rhizobium spp. Transgenic Research, 20(2), 377-386.
- Tricault, Y., Fealy, R., Colbach, N. and Mullins, E. (2011). Towards an optimal management regime to facilitate the coexistence of GM herbicide tolerant and non-GM oilseed rape. European Journal of Agronomy, 34, 26-34.
- Wendt, T. and Mullins, E. (2011). Future challenges and prospects. In: Genetics, Genomics and Breeding of Potato (Eds. J. Bradeen and C. Kole), CRC Press, Baton Rouge, ISBN: 9781578087150.
